International Journal of Herbs and Pharmacological Research IJHPR, 2012, 1(1):18-23
www.antrescentpub.com
RESEARCH PAPER:
A STUDY ON THE EFFECT OF MONDIA WHITEI ON ORGAN AND BODY WEIGHT OF WISTAR RATS
Ihongbe JC, *Salisu AA, Bankole JK, Obiazi AA, and Obiazi AA, and 3Festus O.
Histopathology Unit; Medical Microbiology Unit; 3Chemical Pathology Unit; Department of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo, Nigeria
*Corresponding Author: akindayommy@gmail.com
Received:12th February, 2012 Accepted:25th March, 2012 Published:30th April, 2012
ABSTRACT
This study investigates the effect of Mondia whitei on body and organ weights. The sixteen Wistar rats (151.67 ± 2.89 grams) involved in the study were divided into four groups; a control (Group A) and three test groups (B, C and D). For 3 weeks, group A (control) received normal feed (growers mash), while groups B-D (test) received graded levels of Mondia whitei (4.5; 9.0 and 13.5g respectively) mixed with growers mash per ration of feed daily. Comparatively, the results showed that body weight gain was highest in the control group (22.40 ± 11.21g) and lowest in test group C (17.86 ± 7.84g). Also, a non-significant variation in organ-weight was observed for the testis. The observed changes on body weight and weights of the liver, kidney and testis were dosage and duration dependent. Thus, Mondia whitei may be important in weight anagement considering its effect on body weight. However, further investigations are required in this regard.
Key Words: Mondia whitei, Herbs, Weight, Obesity, Public Health issues
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